The goal of this clinical trial is to learn more about the efficacy of an investigational medication when combined with either Daratumumab and Pomalidomide or Daratumumab alone, and compare the efficacy to another regimen, Daratumumab, Pomalidomide and Dexamethasone.
This trial is currently open and accepting patients.
This trial is organized into 28-day cycles. Participants in this trial will be randomly assigned in to one of three different groups, or arms. Participants in all arms may receive pre-treatment medications to help minimize the risk of side effects from the study drugs.
The investigational medication being studied is a type of drug called a bispecific antibody. Bispecific antibodies are drugs that have two different targets. This investigational medication’s two targets are CD3, a receptor found on our own T cells, and GPRC5D, a protein found on the surface of some myeloma cells. The investigational medication is being evaluated to determine if once in the body, it will draw the body’s T cells and myeloma cells closer together, resulting in T cell activation and myeloma cell death.
The following criteria is a partial list of reasons why patients may be eligible to participate in this clinical trial. Further evaluation with a medical professional is required.
Enrollment: 810 patients (estimated)View More
Read the latest news and updates on this trial.
September 26, 2022
Click below to watch a short video about Multiple Myeloma clinical trial participation.
View all clinical trial locations sorted by state.
Ann Arbor, MI
New York, NY
Chapel Hill, NC
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