A Phase 2 Adaptive Study of Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients With High-Risk Smoldering Multiple Myeloma

What's the purpose of this trial?

To assess the remission rate of daratumumab, carfilzomib, and dexamethasone (DKd) in patients with high-risk (HR) smoldering multiple myeloma (SMM) by determining the minimal residual disease (MRD) negative complete response (CR) rate by up to 12 cycles of induction therapy using flow cytometry.

This is an upcoming trial that has not yet started accepting patients.


What will happen during the trial?

Additional Trial Information

Phase 2

Enrollment: 59 patients (estimated)

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Trial Locations

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Maryland

National Institutes of Health (NIH)

Bethesda, MD

Not Yet Accepting
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