Daratumumab Based Response Adapted Therapy for Older Adults With Newly Diagnosed Multiple Myeloma DARATUMUMAB BASED RESPONSE ADAPTED THERAPY

What's the purpose of this trial?

In this response adapted approach, older adults with newly diagnosed symptomatic multiple myeloma will receive daratumumab and dexamethasone for 2 months. Patients who achieve a partial response or better will continue on daratumumab. Patients who achieve less than a partial response will have lenalidomide or bortezomib added to their therapy. Patients who experience progressive disease on daratumumab after the initial 2 months of monotherapy or on the combination of daratumumab and either lenalidomide or bortezomib will come off study.

This trial is currently open and accepting patients.

What will happen during the trial?

Additional Trial Information

Phase 2

Enrollment: 32 patients (estimated)

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Trial Locations

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Moffitt Cancer Center Magnolia Campus

Tampa, FL

Open and Accepting
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