Bortezomib

VELCADE®

Overview

Bortezomib is a kind of medication called a proteasome inhibitor that interferes with the growth and spread of cancer cells in the body. Bortezomib is used to treat multiple myeloma and mantle cell lymphoma.

SparkCures ID 1
Developed By Takeda Oncology
Brand Name Velcade®
Generic Name Bortezomib
Treatment Classifications

Clinical Trials

All Clinical Trials

View all active clinical trials around the US.

Verified
Phase 3, Randomized Study comparing Bortezomib, Lenalidomide, and Dexamethasone (VRd) followed by an investigational CAR-T versus VRd followed by Lenalidomid...
CARTITUDE-5
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Verified
Phase 3 Clinical Trial Comparing the Safety and Effectiveness of Iberdomide, Daratumumab and Dexamethasone VS Daratumumab, Bortezomib, and Dexamethasone in P...
EXCALIBER RRMM
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Verified
Phase 3 Clinical Trial Evaluating the Safety and Effectiveness of Investigational Drug Mezigdomide in Combination with Bortezomib and Dexamethasone Compared ...
SUCCESSOR-1
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Verified
A Phase 3, Open-Label Study of Elranatamab Monotherapy Versus Elotuzumab, Pomalidomide, Dexamethasone (EPd) Or Pomalidomide, Bortezomib, Dexamethasone (PVd) ...
MAGNETISMM-32
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Verified
A Phase 3 Randomized Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Parti...
MAJESTEC-9
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Verified
Carfilzomib, Lenalidomide, and Dexamethasone Versus Bortezomib, Lenalidomide and Dexamethasone (KRd vs. VRd) in Patients With Newly Diagnosed Multiple Myelom...
COBRA
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Verified
A Phase III Study of Belantamab Mafodotin plus Pomalidomide and Dexamethasone vs Pomalidomide, Bortezomib and Dexamethasone in Participants with Relapsed / R...
DREAMM8
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Verified
A Study of Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone in Patients With Newly-Diagnosed Multiple Myeloma (ADVANCE)
ADVANCE
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Verified
Daratumumab-Based Therapy for the Treatment of Newly Diagnosed Multiple Myeloma With Kidney Failure
DARATUMUMAB FOR PATIENTS WITH KIDNEY FAILURE
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Verified
A Phase 1 Study of Belantamab Mafodotin Plus Standard of Care in Newly Diagnosed Multiple Myeloma
DREAMM9
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SparkCures Verified Accurate, up-to-date information. Learn more

A Study of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autole...
CARTITUDE-6
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Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE ...
EQUATE
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A Phase III Randomized Trial for Newly Diagnosed Multiple Myeloma (NDMM) Patients Considered Frail or in a ...
TRIPLET INDUCTION + 1 OR 2-DRUG MAINTENANCE
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A Randomized Phase 2 Study of Daratumumab-Selinexor-Velcade-Dexamethasone (Dara-SVD) for High-Risk Newly Di...
DARA-SVD VS. DARA-RVD
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MRD-Guided Sequential Therapy For Deep Response in Newly Diagnosed Multiple Myeloma - MASTER-2 Trial
MASTER-2
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A Phase II Study of CyBorD (Cyclophosphamide, Bortezomib, Dexamethasone) Plus Daratumumab for Patients With...
CYBORD PLUS DARATUMUMAB
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Bortezomib and Pembrolizumab With or Without Pelareorep for the Treatment of Relapsed or Refractory Multipl...
AMBUSH
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Minimal Residual Disease Response-adapted Deferral of Transplant in Dysproteinemia (MILESTONE)
MILESTONE
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Bortezomib, Isatuximab, Cyclophosphamide and Dexamethasone Induction in Transplant-Eligible Multiple Myelom...
VICD
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DARA RVD For High Risk SMM
PRISM
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Study of SubQ Dara With Dose-Attenuated Bortezomib, Lenalidomide, Dexamethasone in Elderly Newly Diagnosed ...
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Iberdomide, Daratumumab, Bortezomib, and Dexamethasone for the Treatment of Newly Diagnosed Multiple Myelom...
IDEAL
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A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments f...
LINVOSELTAMAB
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A Protocol to Assess the Safety, Efficacy, and Pharmacokinetics of Continuous Subcutaneous Administration o...
STAR-LLD
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Pilot Study of Daratumumab in Combination With Bortezomib, Cyclophosphamide, and Dexamethasone (Dara-CyBorD...
DARATUMUMAB FOR PATIENTS WITH RENAL FAILURE
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Untreated / Newly Diagnosed Multiple Myeloma

The following is a listing of clinical trials for patients with multiple myeloma who have been newly diagnosed or have not yet received treatment.

Verified
Phase 3, Randomized Study comparing Bortezomib, Lenalidomide, and Dexamethasone (VRd) followed by an investigational CAR-T versus VRd followed by Lenalidomid...
CARTITUDE-5
View Trial
Verified
Carfilzomib, Lenalidomide, and Dexamethasone Versus Bortezomib, Lenalidomide and Dexamethasone (KRd vs. VRd) in Patients With Newly Diagnosed Multiple Myelom...
COBRA
View Trial
Verified
A Study of Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone in Patients With Newly-Diagnosed Multiple Myeloma (ADVANCE)
ADVANCE
View Trial
Verified
Daratumumab-Based Therapy for the Treatment of Newly Diagnosed Multiple Myeloma With Kidney Failure
DARATUMUMAB FOR PATIENTS WITH KIDNEY FAILURE
View Trial
Verified
A Phase 1 Study of Belantamab Mafodotin Plus Standard of Care in Newly Diagnosed Multiple Myeloma
DREAMM9
View Trial

SparkCures Verified Accurate, up-to-date information. Learn more

A Study of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autole...
CARTITUDE-6
View Trial
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE ...
EQUATE
View Trial
A Phase III Randomized Trial for Newly Diagnosed Multiple Myeloma (NDMM) Patients Considered Frail or in a ...
TRIPLET INDUCTION + 1 OR 2-DRUG MAINTENANCE
View Trial
A Randomized Phase 2 Study of Daratumumab-Selinexor-Velcade-Dexamethasone (Dara-SVD) for High-Risk Newly Di...
DARA-SVD VS. DARA-RVD
View Trial
MRD-Guided Sequential Therapy For Deep Response in Newly Diagnosed Multiple Myeloma - MASTER-2 Trial
MASTER-2
View Trial
A Phase II Study of CyBorD (Cyclophosphamide, Bortezomib, Dexamethasone) Plus Daratumumab for Patients With...
CYBORD PLUS DARATUMUMAB
View Trial
Minimal Residual Disease Response-adapted Deferral of Transplant in Dysproteinemia (MILESTONE)
MILESTONE
View Trial
Bortezomib, Isatuximab, Cyclophosphamide and Dexamethasone Induction in Transplant-Eligible Multiple Myelom...
VICD
View Trial
Study of SubQ Dara With Dose-Attenuated Bortezomib, Lenalidomide, Dexamethasone in Elderly Newly Diagnosed ...
View Trial
Iberdomide, Daratumumab, Bortezomib, and Dexamethasone for the Treatment of Newly Diagnosed Multiple Myelom...
IDEAL
View Trial
Early Relapse Multiple Myeloma

The following is a listing of clinical trials for patients with multiple myeloma who have received one to two prior lines of therapy.

Verified
Phase 3 Clinical Trial Comparing the Safety and Effectiveness of Iberdomide, Daratumumab and Dexamethasone VS Daratumumab, Bortezomib, and Dexamethasone in P...
EXCALIBER RRMM
View Trial
Verified
Phase 3 Clinical Trial Evaluating the Safety and Effectiveness of Investigational Drug Mezigdomide in Combination with Bortezomib and Dexamethasone Compared ...
SUCCESSOR-1
View Trial
Verified
A Phase 3, Open-Label Study of Elranatamab Monotherapy Versus Elotuzumab, Pomalidomide, Dexamethasone (EPd) Or Pomalidomide, Bortezomib, Dexamethasone (PVd) ...
MAGNETISMM-32
View Trial
Verified
A Phase III Study of Belantamab Mafodotin plus Pomalidomide and Dexamethasone vs Pomalidomide, Bortezomib and Dexamethasone in Participants with Relapsed / R...
DREAMM8
View Trial

SparkCures Verified Accurate, up-to-date information. Learn more

A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments f...
LINVOSELTAMAB
View Trial
A Protocol to Assess the Safety, Efficacy, and Pharmacokinetics of Continuous Subcutaneous Administration o...
STAR-LLD
View Trial
Late Relapse Multiple Myeloma

The following is a listing of clinical trials for patients with multiple myeloma who have received three or more prior lines of therapy.

Verified
Phase 3 Clinical Trial Evaluating the Safety and Effectiveness of Investigational Drug Mezigdomide in Combination with Bortezomib and Dexamethasone Compared ...
SUCCESSOR-1
View Trial
Verified
A Phase 3, Open-Label Study of Elranatamab Monotherapy Versus Elotuzumab, Pomalidomide, Dexamethasone (EPd) Or Pomalidomide, Bortezomib, Dexamethasone (PVd) ...
MAGNETISMM-32
View Trial
Verified
A Phase III Study of Belantamab Mafodotin plus Pomalidomide and Dexamethasone vs Pomalidomide, Bortezomib and Dexamethasone in Participants with Relapsed / R...
DREAMM8
View Trial

SparkCures Verified Accurate, up-to-date information. Learn more

Bortezomib and Pembrolizumab With or Without Pelareorep for the Treatment of Relapsed or Refractory Multipl...
AMBUSH
View Trial
A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments f...
LINVOSELTAMAB
View Trial
A Protocol to Assess the Safety, Efficacy, and Pharmacokinetics of Continuous Subcutaneous Administration o...
STAR-LLD
View Trial
Smoldering Myeloma

The following is a listing of clinical trials for patients with Smoldering Myeloma.

DARA RVD For High Risk SMM
PRISM
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Monoclonal Gammopathy of Undetermined Significance (MGUS)

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