A Study of Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone in Patients With Newly-Diagnosed Multiple Myeloma ADVANCE

What's the purpose of this trial?

This study is being done to find out whether carfilzomib, lenalidomide, and dexamethasone (KRD) or KRD and Daratumumab (KRD+DARA) might be safer and more effective ways of controlling multiple myeloma than the stand or care treatment, which is lenalidomide, bortexomib, and dexamethasone (VRD).

This trial is currently open and accepting patients.


What will happen during the trial?

Additional Trial Information

Phase 2

Enrollment: 462 patients (estimated)

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Trial Locations

All Trial Locations

View all clinical trial locations sorted by state.

Florida

Sylvester Comprehensive Cancer Center University of Miami Health System

Miami, FL

Open and Accepting

Moffitt Cancer Center Magnolia Campus

Tampa, FL

Not Yet Accepting

Illinois

Rush University Medical Center

Chicago, IL

Not Yet Accepting

Iowa

Holden Comprehensive Cancer Center University of Iowa Hospitals and Clinics

Iowa City, IA

Not Yet Accepting

New Jersey

Memorial Sloan Kettering Cancer Center

Basking Ridge, NJ

Temporarily Suspended

Memorial Sloan Kettering Cancer Center

Middletown, NJ

Temporarily Suspended

Memorial Sloan Kettering Bergen

Montvale, NJ

Temporarily Suspended

New York

Memorial Sloan Kettering Cancer Center

New York, NY

Temporarily Suspended

Roswell Park Cancer Institute

Buffalo, NY

Not Yet Accepting

Memorial Sloan Kettering Cancer Center

Commack, NY

Temporarily Suspended

Stony Brook University Hospital

Stony Brook, NY

Not Yet Accepting

Memorial Sloan Kettering Cancer Center Nassau

Uniondale, NY

Open and Accepting

Memorial Sloan Kettering Cancer Center Westchester in West Harrison

West Harrison, NY

Temporarily Suspended

Texas

MD Anderson Cancer Center The University of Texas

Houston, TX

Not Yet Accepting

Utah

Huntsman Cancer Institute University of Utah

Salt Lake City, UT

Not Yet Accepting
Interested in this trial?
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