Hypomethylating Agents (HMA)

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Myeloma Clinical Trials

The following is a listing of myeloma clinical trials associated with this tag.

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A Master Protocol for Biomarker-Based Treatment of AML (The Beat AML Trial)
THE BEAT AML TRIAL
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A Phase 1 Study of Adding Venetoclax to a Reduced Intensity Conditioning Regimen and to Maintenance in Comb...
VENETOCLAX IN PRE- AND POST-TRANSPLANT THERAPY
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A Phase 1b/2, Open-Label, Dose Finding, and Expansion Study of the Bcl-2 Inhibitor BGB-11417 in Patients Wi...
BGB-11417
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A Phase 2 Study of Fludarabine, Cytarabine, Filgrastim-sndz,Gemtuzumab Ozogamicin and Idarubicin in Newly D...
GEMTUZUMAB AS PART OF CHEMOTHERAPY
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A Phase 2 Trial Investigating Decitabine in Combination With a JAK-Inhibitor as a Bridge to Allogeneic Hema...
DECITABINE PLUS A JAK-INHIBITOR
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A Phase I Study of Venetoclax in Combination With Cytotoxic Chemotherapy, Including Calaspargase Pegol, for...
VENETOCLAX BASKET TRIAL
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A Phase I/II Study of Azacitidine, Venetoclax, and Gilteritinib for Patients With Acute Myeloid Leukemia or...
AZACITIDINE, VENETOCLAX, AND GILTERITINIB
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A Phase I/II Study of Quizartinib in Combination With Decitabine and Venetoclax for the Treatment of Patien...
QUIZARTINIB WITH DECITABINE AND VENETOCLAX
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A Phase I/II Study of Venetoclax in Combination With ASTX727 (Cedazuridine/Decitabine) in Treatment-Naïve H...
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A Phase I/II Study of Venetoclax in Combination With Azacitidine in Relapsed/Refractory High-Risk Myelodysp...
VENETOCLAX PLUS AZACITIDINE
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A Phase I/II Trial of Pre-emptive Therapy With DEC-C to Improve Outcomes in MDS Patients With Measurable Re...
DEC-C POST-TRANSPLANT
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A Phase Ib Study of Oral Decitabine/Cedazuridine as Maintenance Therapy Following Allogeneic Hematopoietic ...
DECITABINE/CEDAZURIDINE AS MAINTENANCE THERAPY
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A Phase Ib/II Study Evaluating Navitoclax After Failure of Hypomethylating Agent and Venetoclax for Treatme...
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A Phase Ib/II Study of APG-115 Alone or in Combination With Azacitidine in Patients With Relapse/Refractory...
APG-115
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A Phase Ib/II Study of APG-2575 in Combination With Azacitidine in Patients With Acute Myeloid Leukemia (AM...
APG-2575 PLUS AZACITIDINE
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A Phase II Study of Cladribine and Low Dose Cytarabine in Combination With Venetoclax, Alternating With Aza...
CLADRIBINE, CYTARABINE AND VENETOCLAX FOR HR-MDS
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A Pilot Study to Evaluate the Feasibility of Post-Hematopoietic Stem Cell Transplant Prophylaxis With Decit...
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A Randomized, Double-blind, Placebo-controlled Phase 3 Study of Tamibarotene Plus Azacitidine Versus Placeb...
SELECT MDS-1
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An Open-label Phase Ib Study of DSP107 for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)
DSP107
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An Open-label, Multicenter, Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Saba...
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Epigenetic Modification for Relapse Prevention: a Dose-finding Study of Vorinostat Used in Combination With...
VORINOSTAT POST-TRANSPLANT
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Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML
LOW DOSE WEEKLY DECITABINE/VENETOCLAX
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Phase 1 Study of SL-401 in Combination With Azacitidine and Venetoclax in Relapsed/Refractory Acute Myeloid...
SL-401
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Phase 1b Study of Pembrolizumab, Decitabine +/- Venetoclax Combination Therapy in Patients With Relapsed or...
PEMBROLIZUMAB, DECITABINE +/- VENETOCLAX
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Phase 1b/2 Clinical Study of the Safety, Tolerability, and Pharmacokinetic and Pharmacodynamic Profiles of ...
TWT-202
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Phase I/II of Venetoclax in Combination With Azacitidine in Treatment Naïve and Relapse Refractory High Ris...
VENETOCLAX PLUS AZACITIDINE
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Phase I/II Study of Azacitidine in Combination With Quizartinib for Patients With Myelodysplastic Syndromes...
AZACITIDINE PLUS QUIZARTINIB
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Phase Ib/II Investigator Initiated Study of the IDH1-Mutant Inhibitor Ivosidenib (AG120) With the BCL2 Inhi...
IVOSIDENIB (AG120)
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Phase II Study of Cladribine Plus Low Dose Cytarabine (LDAC) Induction Followed By Consolidation With Cladr...
CYTARABINE ALTERNATING WITH DECITABINE
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Phase II Study of Clinical Efficacy of Venetoclax in Combination With Azacitidine in Patients With Therapy ...
VENETOCLAX AND AZACITIDINE FOR THERAPY-RELATED MDS
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Proof-Of-Concept Study of Metabolically Optimized, Non-Cytotoxic 5-Azacitidine and Decitabine Epigenetic Th...
AZACITIDINE AND DECITABINE
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TakeAim Leukemia: A Phase 1/2A, Open Label Dose Escalation and Expansion Study of Orally Administered CA-49...
TAKEAIM
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The ABNL-MARRO 001 Study: A Phase 1/2 Study of Active Myeloid Target Compound Combinations in MDS/MPN Overl...
ABNL-MARRO
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Venetoclax in Combination With ASTX727, an All-ORal Therapy for Chronic Myelomonocytic Leukemia and Other M...
VENETOCLAX IN COMBINATION WITH ASTX727
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Multiple Myeloma
Smoldering Myeloma
Monoclonal Gammopathy of Undetermined Significance (MGUS)

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