A Study of Venetoclax and Dexamethasone Compared With Pomalidomide and Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma CANOVA

What's the purpose of this trial?

A study designed to evaluate the safety and efficacy of venetoclax plus dexamethasone (VenDex) compared with pomalidomide plus dexamethasone (PomDex) in participants with t(11;14)-positive Relapsed or Refractory Multiple Myeloma.

This trial is currently open and accepting patients.

What will happen during the trial?


Additional Trial Information

Phase 3

Enrollment: 244 patients (estimated)

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Trial Locations

All Trial Locations

View all clinical trial locations sorted by state.


University of Arizona Comprehensive Cancer Center

Tucson, AZ

Open and Accepting


VA Central California Health

Fresno, CA

Open and Accepting

UCLA Jonsson Comprehensive Cancer Center University of California Los Angeles

Los Angeles, CA

Open and Accepting


VA Eastern Colorado Healthcare System

Aurora, CO

Open and Accepting


Mayo Clinic (Jacksonville)

Jacksonville, FL

Open and Accepting

Cleveland Clinic Florida

Weston, FL

Open and Accepting



Boston Medical Center

Boston, MA

Open and Accepting


Barbara Ann Karmanos Cancer Institute Wayne State University

Detroit, MI

Open and Accepting

Henry Ford Hospital

Detroit, MI

Open and Accepting


Mayo Clinic (Rochester)

Rochester, MN

Open and Accepting

New York


Cleveland Clinic Taussig Cancer Institute

Cleveland, OH

Open and Accepting

Cleveland Clinic (Fairview Hospital)

Cleveland, OH

Open and Accepting


MD Anderson Cancer Center The University of Texas

Houston, TX

Open and Accepting


Huntsman Cancer Institute University of Utah

Salt Lake City, UT

Open and Accepting


VA Puget Sound Health Care System

Seattle, WA

Open and Accepting

Trial Links

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