Safety Study of Unlicensed, Investigational Cord Blood Units Manufactured by the NCBP for Unrelated Transplantation

Overview

The primary aim of this study is to examine the safety of administration of the unlicensed investigational NCBP hematopoietic progenitor cell-cord blood (HPC-CORD BLOOD) products in a multi-institution setting. Therefore, the study will evaluate prospectively the incidence of serious adverse reactions as well as the incidence of all infusion related reactions after administration of the unlicensed, investigational NCBP CBU.

SparkCures ID 358
Trial Phase Phase 2
Enrollment Information Not Available
Treatments
Tags
  • Allogeneic Stem Cell Transplant
Trial Sponsors
  • New York Blood Center
NCT Identifier

NCT01656603

Am I Eligible?

The following criteria is a partial list of reasons why patients may or may not be eligible to participate in this clinical trial. Further evaluation with a medical professional will be required to determine full eligibility.

The following criteria is provided for health care professionals.

Inclusion Criteria:

  1. Diagnosis: Patients with disorders affecting the hematopoietic system that are inherited, acquired, or result from myeloablative treatment.
  2. Patients: Patients of any age and either gender
  3. Cord blood product manufactured by the NCBP (at least one, if the graft contains more than one units)

Exclusion Criteria:

  1. Patients who are receiving licensed cord blood products (only)
  2. Patients who are receiving unlicensed cord blood products from other banks (only)
  3. Patients who are transplanted at non-US transplant centers
  4. Patients who are receiving cord blood products that will be "manipulated" post-thaw (e.g., ex vivo expansion, incubation in vitro, etc.)

US Trial Locations

Accepting Patients

The following is a listing of trial locations that are open and accepting patients.

Verified Memorial Sloan Kettering Cancer Center

SparkCures Verified Accurate, up-to-date information. Learn more


Children's of Alabama

Birmingham, AL

Stephenson Cancer Center

Oklahoma City, OK

University of Mississippi Medical Center

Jackson, MS

Steven and Alexandra Cohen Children's Medical Center

North New Hyde Park, NY

University of Rochester Medical Center James P. Wilmot Cancer Center

Rochester, NY

Akron Children's Hospital

Akron, OH

Cincinnati Children's Hospital Medical Center

Cincinnati, OH

University Hospitals Seidman Cancer Center at UH Case Medical

Cleveland, OH

Children's Hopsital of Pittsburgh of UPMC

Pittsburgh, PA

Cancer Treatment Centers of America Southwestern Regional Medical Center

Tulsa, OK

Mayo Clinic (Rochester)

Rochester, MN

Children's Hospital of Philadelphia

Philadelphia, PA

St. Jude Children's Research Center

Memphis, TN

Children's Medical Center of Dallas

Dallas, TX

Cook Children's Medical Center

Fort Worth, TX

Texas Children's Cancer Center

Houston, TX

Texas Transplant Institute

San Antonio, TX

UVA Cancer Center University of Virginia Health System

Charlottesville, VA

Massey Cancer Center Virginia Commonwealth University (VCU Health)

Richmond, VA

St. Louis University Hospital

St. Louis, MO

Henry Ford Hospital

Detroit, MI

Phoenix Children's Hospital

Phoenix, AZ

Rady Children's Hospital

San Diego, CA

University of Colorado Cancer Center Anschutz Cancer Pavilion

Aurora, CO

The Children's Hospital of Colorado

Aurora, CO

Presbyterian/St. Luke's Medical Center

Denver, CO

Children's National Medical Center

Washington, DC

Alfred I. DuPont Hospital for Children

Wilmington, DE

All Children's Hospital

St. Petersburg, FL

Florida Hospital (Florida Center for Cellular Therapy)

Orlando, FL

Nemour's Children's Clinic and Hospital

Jacksonville, FL

Helen DeVos Children's Hospital

Grand Rapids, MI

Northside Hospital

Atlanta, GA

Children's Healthcare of Atlanta

Atlanta, GA

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, IL

Loyola University Medical Center Cardinal Bernardin Cancer Center

Maywood, IL

Midwestern Regional Medical Center

Zion, IL

KentuckyOne Health - James Graham Brown Cancer Center

Louisville, KY

Children's Hospital of Wisconsin

Milwaukee, WI

Alabama
Children's of Alabama

Birmingham, AL

Arizona
Phoenix Children's Hospital

Phoenix, AZ

California
Rady Children's Hospital

San Diego, CA

Colorado
University of Colorado Cancer Center Anschutz Cancer Pavilion

Aurora, CO

The Children's Hospital of Colorado

Aurora, CO

Presbyterian/St. Luke's Medical Center

Denver, CO

Delaware
Alfred I. DuPont Hospital for Children

Wilmington, DE

Florida
Nemour's Children's Clinic and Hospital

Jacksonville, FL

Florida Hospital (Florida Center for Cellular Therapy)

Orlando, FL

All Children's Hospital

St. Petersburg, FL

Georgia
Northside Hospital

Atlanta, GA

Children's Healthcare of Atlanta

Atlanta, GA

Illinois
Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, IL

Loyola University Medical Center Cardinal Bernardin Cancer Center

Maywood, IL

Midwestern Regional Medical Center

Zion, IL

Indiana
Kentucky
KentuckyOne Health - James Graham Brown Cancer Center

Louisville, KY

Maryland
Massachusetts
Michigan
Henry Ford Hospital

Detroit, MI

Helen DeVos Children's Hospital

Grand Rapids, MI

Minnesota
Mayo Clinic (Rochester)

Rochester, MN

Mississippi
University of Mississippi Medical Center

Jackson, MS

Missouri
Verified Alvin J. Siteman Cancer Center Washington University Medical Campus

SparkCures Verified Accurate, up-to-date information. Learn more


St. Louis University Hospital

St. Louis, MO

New York
Verified Memorial Sloan Kettering Cancer Center

SparkCures Verified Accurate, up-to-date information. Learn more


Steven and Alexandra Cohen Children's Medical Center

North New Hyde Park, NY

University of Rochester Medical Center James P. Wilmot Cancer Center

Rochester, NY

Ohio
Akron Children's Hospital

Akron, OH

Cincinnati Children's Hospital Medical Center

Cincinnati, OH

University Hospitals Seidman Cancer Center at UH Case Medical

Cleveland, OH

Oklahoma
Stephenson Cancer Center

Oklahoma City, OK

Cancer Treatment Centers of America Southwestern Regional Medical Center

Tulsa, OK

Pennsylvania
Children's Hospital of Philadelphia

Philadelphia, PA

Children's Hopsital of Pittsburgh of UPMC

Pittsburgh, PA

South Carolina
Tennessee
St. Jude Children's Research Center

Memphis, TN

Texas
Children's Medical Center of Dallas

Dallas, TX

Cook Children's Medical Center

Fort Worth, TX

Texas Children's Cancer Center

Houston, TX

Texas Transplant Institute

San Antonio, TX

Virginia
UVA Cancer Center University of Virginia Health System

Charlottesville, VA

Massey Cancer Center Virginia Commonwealth University (VCU Health)

Richmond, VA

Washington
Washington, D.C.
Children's National Medical Center

Washington, DC

Wisconsin
Verified UW Carbone Cancer Center University of Wisconsin Health

SparkCures Verified Accurate, up-to-date information. Learn more


Children's Hospital of Wisconsin

Milwaukee, WI

Resources

There are no resources, links or videos to display for this clinical trial.

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