CC-92480 is a novel cereblon E3 ligase modulator (CELMoD) agent designed for rapid, maximal degradation of Ikaros and Aiolos. In vitro, it has enhanced antiproliferative and tumoricidal activity in MM cell lines, including those resistant to lenalidomide (LEN) and pomalidomide (POM), with strong immune stimulatory activity.
| SparkCures ID | 307 |
|---|---|
| Developed By | Celgene Corporation |
| Generic Name | CC-92480 |
| Treatment Classifications |
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June 01, 2020
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