Autologous Transplant is a type of stem cell transplant that utilizes the patient's pre-collected own stem cell to rescue the bone marrow from the toxic effect of a very high dose chemotherapy.
SparkCures ID | 21 |
---|---|
Generic Name | Autologous Stem Cell Transplant |
Treatment Classifications |
View all active clinical trials around the US.
The following is a listing of clinical trials for patients with multiple myeloma who have been newly diagnosed or have not yet received treatment.
The following is a listing of clinical trials for patients with multiple myeloma who have received one to two prior lines of therapy.
SparkCures Verified Accurate, up-to-date information. Learn more
The following is a listing of clinical trials for patients with multiple myeloma who have received three or more prior lines of therapy.
SparkCures Verified Accurate, up-to-date information. Learn more
June 07, 2022
The trial enrolled 722 patients, aged 18 to 65 years, with newly diagnosed MM. Dr Richardson noted that this trial has the highest African American participation of any phase 3 study in this setting to date (18.8%).
All patients received 3 cycles of RVd followed by stem cell collection (reserved for possible ASCT if disease progressed). Patients were then randomly assigned to receive 5 more cycles of RVd (RVd-alone arm, n=357) or melphalan at 200 mg/m2, followed by ASCT and 2 more cycles of RVd (RVd+ASCT arm, n=365). Patients in both arms received lenalidomide maintenance until disease progression or intolerable drug toxicity.
January 15, 2019
October 09, 2018