This phase I trial studies the best dose and side effects of mephalan in treating patients with multiple myeloma who are undergoing stem cell transplant. Chemotherapy drugs, such as mephalan, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial uses a new method of dosing that is based on analysis of each individual's blood levels of melphalan after receiving a part of the dose, termed pharmacokinetic analysis. This may help to learn more about how to dose melphalan correctly and which patients are likely to benefit from a personalized dose.
SparkCures ID | 1129 |
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Trial Phase | Phase 1 |
Enrollment | 90 Patients |
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The following criteria is a partial list of reasons why patients may or may not be eligible to participate in this clinical trial. Further evaluation with a medical professional will be required to determine full eligibility.
Inclusion Criteria:
Exclusion Criteria:
The following criteria is provided for health care professionals.
Inclusion Criteria:
Exclusion Criteria:
The following is a listing of trial locations that are not currently open and accepting patients.
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