The following criteria is provided for health care professionals.

Inclusion Criteria:

• Subject must have a confirmed diagnosis of:
  1. Previously Relapsed or refractory acute leukemia (myeloid or lymphoid)
  2. Acute leukemia in first remission at high-risk for recurrence
  3. Chronic myelogenous leukemia in chronic, accelerated phase or blast-crisis
  4. Recurrent or refractory malignant lymphoma or Hodgkin lymphoma
  5. Chronic lymphocytic leukemia, relapsed or with poor prognostic features
  6. Multiple myeloma
  7. Myelodysplastic syndrome
  8. Chronic myeloproliferative disease
  9. Hemoglobinopathies
  10. Aplastic anemia
  11. Other hematological disorder in need of allogeneic transplant (e.g. blastoid dendritic cell neoplasm)
• Age ≥ 18 years
• Likely to benefit from allogeneic transplant in the opinion of the transplant physician
• An HLA-identical related or unrelated donor cannot be identified within an appropriate time frame.
• Karnofsky (KPS) Performance status of >= 70%
• Acceptable organ function as defined below: Serum bilirubin: < 2.0mg/dL ALT(SGPT): < 3 X upper limit of normal Creatinine Clearance: > 50 mL/min/1.73m2 (as estimated by the modified MDRD equation)
• Ability to understand and the willingness to sign a written informed consent document

Exclusion Criteria:

• Life expectancy is severely limited by concomitant illness or uncontrolled infection
• Severely decreased Left Ventricular Ejection Fraction (LVEF) or impaired pulmonary function tests (PFT's)
• Evidence of chronic active hepatitis or cirrhosis
• Uncontrolled HIV disease
• Pregnant or lactating