Defining Inflammatory Biomarkers of Cardiovascular Disease in Patients with Myelodysplastic Syndromes BIOMARKERS OF CARDIOVASCULAR DISEASE IN MDS

What's the purpose of this trial?

Why Is This Research Study Being Conducted? * The study wants to find out why people with a type of blood cancer called myelodysplastic syndromes (MDS) are more likely to have heart problems like heart disease and stroke. * Researchers also want to see if certain proteins related to inflammation in the body can help predict these heart issues in MDS patients. * By understanding this better, researchers hope to find new ways to detect and manage heart disease risks in people with MDS

This trial is currently open and accepting patients.

What will happen during the trial?

You may be able to join this trial if you:

The following criteria is a partial list of reasons why patients may be eligible to participate in this clinical trial. Further evaluation with a medical professional is required.

Inclusion Criteria:

* Age ≥18 years
* Histologically confirmed diagnosis of MDS by bone marrow biopsy morphology, using the 2022 World Health Organization (WHO) classification for myeloid neoplasms
* Eastern Cooperative Oncology Group (ECOG) performance status ≤3
* Expected survival of at least 6 months
* Ability to provide consent

Exclusion Criteria:

* Cases meeting 2022 WHO criteria of MDS with excess blasts 2 as initial diagnosis
* Hematopoietic stem cell transplantation expected within 6 months

Additional Trial Information

Enrollment: 30 patients (estimated)

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Trial Locations

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Vermont

University of Vermont Medical Center

Burlington, VT

Open and Accepting
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