A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors REPOTRECTINIB

What's the purpose of this trial?

This is a Phase 1, open-label, fixed-sequence study to evaluate the potential drug-drug interaction (DDI) effect of repotrectinib on drug transporters (metformin, digoxin and rosuvastatin) following multiple dose administration of repotrectinib in patients with advanced cancer harboring ROS1 and NTRK1 Rearrangements.

This trial is currently open and accepting patients.

Additional Trial Information

Phase 1

Enrollment: 12 patients (estimated)

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Trial Locations

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Gabrail Cancer Center Research

Canton, OH

Open and Accepting
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