Systematic Light Exposure Effects on Circadian Rhythms Entrainment, Inflammation, Neutropenic Fever and Symptom Burden Among Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation AMBIENT LIGHT

What's the purpose of this trial?

The aim of this multi-site randomized control trial will be is to assess the impact Systematic lighting on circadian rhythm entrainment, Inflammation, Neutropenic Fever and Symptom Burden among Multiple Myeloma Patients undergoing Autologous Stem Cell Transplantation. To achieve this aim, 200 multiple myeloma patients will receive one of two different light-treatments that are designed to promote circadian rhythm alignment. While receiving these light treatments, participants' sleep efficiency, urine melatonin levels, blood inflammatory cytokine levels and symptoms will be assessed over a 2-month period.

This trial is currently open and accepting patients.

What will happen during the trial?

You may be able to join this trial if you:

The following criteria is a partial list of reasons why patients may be eligible to participate in this clinical trial. Further evaluation with a medical professional is required.

Inclusion Criteria:

* Multiple Myeloma diagnosis
* Scheduled to undergo their first Autologous Stem Cell Transplant procedure.
* 21years or older
* Able to provide informed consent.
* English-language proficient

Exclusion Criteria:

* Previous Autologous Stem Cell Transplant procedure
* Pregnancy
* Eye diseases which limit the ability of light to be processed
* Secondary cancer diagnosis within the last 5 years
* Severe sleep disorders
* History of bipolar disorder or manic episodes
* Severe psychological impairment
* Previous use of light therapy
* Active infection including COVID-19 infection

Additional Trial Information

Phase 0

Enrollment: 200 patients (estimated)

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Trial Locations

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New York

Memorial Sloan Kettering Cancer Center

New York, NY

Not Yet Accepting

Mount Sinai Hospital Tisch Cancer Institute

New York, NY

Open and Accepting
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