The purpose of this study is to find out whether combination treatment with the study drugsbelantamab mafodotin and nirogacestat is a safe treatment for people who have relapsed orrefractory multiple myeloma. The researchers will test different doses of belantamab mafodotinto find the safest dose to give with nirogacestat. They also want to find out whetherbelantamab mafodotin plus nirogacestat is an effective treatment for this type of bone marrowcancer, and will do tests that show whether the study treatment slows or stops the growth ofcancer.
This trial is currently open and accepting patients.
The following criteria is a partial list of reasons why patients may be eligible to participate in this clinical trial. Further evaluation with a medical professional is required.
Inclusion Criteria:
Exclusion Criteria:
Phase 1
Enrollment: 30 patients (estimated)
View MoreView all clinical trial locations sorted by state.
We know how difficult and confusing this process can be. If you are interested in this clinical trial or have questions, you can call us at any time. You can also send us a direct message with questions.
(888) 828-2206If you are interested in keeping an eye on this trial, you can add it to your list of favorite trials. We'll send you alerts when this trial is updated.
You can explore trial locations from around the US and connect directly with a trial coordinator.
Find Nearby LocationsYou can print an overview of this trial to take in to your next appointment. Your doctor can help you understand if this trial may be right for you.
Still need help? Send us a message
Learn more about how we work with trial sponsors