Study of CAR-T Therapy in Older Patients

Verified

Overview

This study is being done to find out how older patients respond to CAR-T cell therapy and how the treatment affects their quality of life.

SparkCures ID 1273
Trial Phase Observational Trial
Enrollment 141 Patients
Tags
  • Post-CAR T
Trial Sponsors
  • Memorial Sloan Kettering Cancer Center
NCT Identifier

NCT04300998

Am I Eligible?

The following criteria is a partial list of reasons why patients may or may not be eligible to participate in this clinical trial. Further evaluation with a medical professional will be required to determine full eligibility.

The following criteria is provided for health care professionals.

Inclusion Criteria:

  • are ≥60 years old (all cohorts)
  • have pathologically confirmed, relapsed refractory lymphoid malignancy or plasma cell disorder receiving a commercial CAR T-cell product (all cohorts)
  • able to speak and understand English (cohort 1 only)

Exclusion Criteria:

  • Any prior commercial or investigational CAR T therapy (all cohorts)
  • Current diagnosis of major Axis I psychiatric disorder (DSM-IV), major depression, bipolar disorder, or schizophrenia, as per medical records or patient report (cohort 1 only)
  • History of a neurological disorder, neurodegenerative disease, or traumatic brain injury with loss of consciousness (>60 minutes), as per medical records or patient report (cohort 1 only)
  • Current ongoing substance abuse and/or history of substance abuse, as per medical records or patient report (cohort 1 only)
 

US Trial Locations

Please visit the ClinicalTrials.gov page for historical site information.

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