Safety, Tolerability and Pharmacokinetics Study of KPG-818 in Hematological Malignancies Subjects
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What's the purpose of this trial?

This is a Phase 1 study to evaluate the safety, pharmacokinetics(PK), and preliminary clinical activity of KPG-818 as a single agent in adult subjects with selected hematological malignancies, including multiple myeloma (MM), mantle cell lymphoma (MCL), follicular lymphoma (FL), diffuse large B-cell lymphoma (DLBCL), indolent lymphoma, adult T-cell leukemia-lymphoma (ATL), or chronic lymphocytic leukemia (CLL).

This trial is currently open and accepting patients.

What will happen during the trial?

This study will assist in identifying appropriate, well tolerated doses that can be administered in subsequent studies in subjects with selected hematological malignancies.

Additional Trial Information

Phase 1

Enrollment: 56 patients (estimated)

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Trial Locations

All Trial Locations

View all clinical trial locations sorted by state.

California

University of California Davis Comprehensive Cancer Center

Sacramento, CA

Open and Accepting

Florida

Boca Raton Clinical Research (BRCR) Medical Center

Plantation, FL

Open and Accepting

Kentucky

Norton Cancer Institute St. Matthews Campus

Louisville, KY

Open and Accepting

New York

New York Cancer and Blood Specialists

Bronx, NY

Open and Accepting

New York Cancer and Blood Specialists

East Patchogue, NY

Open and Accepting

New York Cancer and Blood Specialists

New York, NY

Open and Accepting

North Shore Hematology Oncology Associates, PC

Port Jefferson Station, NY

Open and Accepting

New York Cancer and Blood Specialists

Port Jefferson Station, NY

Open and Accepting

New York Cancer and Blood Specialists

Riverhead, NY

Open and Accepting

Oregon

Providence Portland Medical Center

Portland, OR

Open and Accepting

Wisconsin

Medical College of Wisconsin Froedtert Hospital

Milwaukee, WI

Open and Accepting
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