This trial is testing which types of anticancer treatments can be safely combined with Belantamab Mafodotin (GSK2857916). It is also testing which doses of Belantamab Mafodotin combined with anticancer treatments are better at treating myeloma than Belantamab Mafodotin on its own.
This trial is currently open and accepting patients.
This trial is randomized, which means that you will be randomly placed into different groups, and this will determine which study drugs you receive.
This trial is open label, which means that both you and the researchers running the study will know which group you are placed in, and which drugs you will be receiving.
This study is being conducted in two different phases:
Each phase will be separated into smaller groups, called substudies. Each substudy will receive Belantamab Mafodotin with one of the other two anticancer therapies, with the exception of a control group in phase 2, which will only receive Belantamab Mafodotin.
Treatments in this trial are organized in 21 day cycles, with patients receiving Belantamab Mafodotin and the other anticancer treatments on day 1 of each cycle as intravenous infusions. Patients can continue to receive experimental treatments until their myeloma gets worse, or they develop bad side effects.
During the first four cycles of this trial, patients must also visit an opthamalogist for eye exams every three weeks. During the entire time patients are a part of this trial, they may not wear contact lenses.
Enrollment: 464 patients (estimated)View More
The following criteria is a partial list of reasons why patients may be eligible to participate in this clinical trial. Further evaluation with a medical professional is required. Create your account or call us today for help (888) 828-2206.
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La Jolla, CA
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