This is a Phase I, FIH, open-label, dose escalation study evaluating safety and efficacy of UCART targeting CS1 in patients with relapsed or refractory multiple myeloma (MM). The purpose of this study is to evaluate the safety and clinical activity of one infusion of UCARTCS1A and to determine the Maximum Tolerated Dose (MTD).
May 5, 2023: Cellectis has given up on its multiple myeloma CAR-T candidate UCARTCS1. With the phase 1 clinical trial two years behind schedule, and heavy investment needed to accelerate enrollment, the off-the-shelf cell therapy specialist is stopping the study and focusing its resources on three other candidates. Learn more
|Trial Phase||Phase 1|
The following criteria is a partial list of reasons why patients may or may not be eligible to participate in this clinical trial. Further evaluation with a medical professional will be required to determine full eligibility.
The following criteria is provided for health care professionals.
Read the latest news and updates on this trial.
July 07, 2020
Cellectis, based in Paris and New York, announced that the U.S. Food and Drug Administration (FDA) has placed a clinical hold on its MELANI-01 trial.
October 30, 2019
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