Maplirpacept

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Overview

Maplirpacept is a type of protein called a fusion protein, which is similar to an antibody. It is designed to target and block a protein called CD47. CD47 is present on cancer cells, and is used by cancer cells to hide from your body’s immune system.

SparkCures ID 344
Developed By Trillium Therapeutics, Inc, a Pfizer company
Generic Name Maplirpacept
Additional Names TTI-622
Treatment Classifications
Treatment Targets

Clinical Trials

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Late Relapse Multiple Myeloma

The following is a listing of clinical trials for patients with multiple myeloma who have received three or more prior lines of therapy.

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A Study of TTI-622 in Combination With Daratumumab Hyaluronidase-fihj in People With Multiple Myeloma
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Smoldering Myeloma
Monoclonal Gammopathy of Undetermined Significance (MGUS)

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