Mezagitamab (TAK-079) is a fully human, non-agonistic, IgG1 cell-depleting monoclonal antibody that binds human CD38 with high affinity.
| SparkCures ID | 310 |
|---|---|
| Developed By | Takeda Oncology |
| Generic Name | Mezagitamab |
| Additional Names | TAK-079 |
| Treatment Classifications | |
| Treatment Targets |
November 13, 2019
In the 14 patients receiving at least 4 cycles of therapy by the time of the data cutoff, the objective response rate (ORR; partial response or better) was 43%, 1 patient's response deepened over time to VGPR, the clinical benefit rate (minimal response or better) was 57%. Within this group, in patients never exposed to anti-CD38 therapy, the ORR was 46%.
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