Normally, your body is continually breaking down and rebuilding your bone. This helps keep your bones strong.

In people with multiple myeloma, the breakdown and rebuilding of your bones can become unbalanced. Over time, this can cause weak spots in the bones and can lead to serious bone problems.

Denosumab (Xgeva®) works by stopping cells that are breaking down bone from becoming overactive and may interrupt the process of bone breakdown.