This is a study of venetoclax, daratumumab, and dexamethasone with and without bortezomib combination therapy to evaluate safety, tolerability, and efficacy of these combinations in participants with relapsed or refractory multiple myeloma.
SparkCures ID | 923 |
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Trial Phase | Phase 1/2 |
Enrollment | 104 Patients |
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The following criteria is a partial list of reasons why patients may or may not be eligible to participate in this clinical trial. Further evaluation with a medical professional will be required to determine full eligibility.
The following criteria is provided for health care professionals.
Inclusion Criteria:
Exclusion Criteria:
For participants in Parts 1 and 2: Previous treatment with daratumumab or other anti-CD38 therapy. For participants in Part 3: Prior daratumumab or other anti-CD38 antibody therapy exposure that meets ANY of the following criteria:
For participants in Part 2 and 3:
History of other active malignancies including myelodysplatic syndromes (MDS) within the past 3 years with the exceptions of:
The following is a listing of trial locations that are open and accepting patients.
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Tampa, FL
Boston, MA
Charlotte, NC
New York, NY
Seattle, WA
The following is a listing of trial locations that are not currently open and accepting patients.
Tampa, FL
Boston, MA
New York, NY
SparkCures Verified Accurate, up-to-date information. Learn more
Charlotte, NC
Seattle, WA
This trial has active trial locations in countries outside of the United States.
Our system currently only provides clinical trial matching services for myeloma patients in the United States.
You can view this clinical trial's international locations by visiting ClinicalTrials.gov. Please be aware that the government website may include information that is inaccurate and/or out-of-date.
There are no resources, links or videos to display for this clinical trial.
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