Isatuximab, Bendamustine, and Prednisone in Refractory Multiple Myeloma

What's the purpose of this trial?

Isatuximab targets and kills CD38-positive myeloma cells in manner similar to rituximab's mechanism of action on CD20-positive lymphoma cells. Based on the synergy between rituximab and bendamustine, as well as the established clinical efficacy of bendamustine and isatuximab as single agents for multiple myeloma, the logical next step is to combine isatuximab with bendamustine and prednisone.

This trial is currently open and accepting patients.


What will happen during the trial?

Additional Trial Information

Phase 1/2

Enrollment: 37 patients (estimated)

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Trial Locations

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Missouri

Alvin J. Siteman Cancer Center Washington University Medical Campus

St. Louis, MO

Open and Accepting
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