The goal of this clinical trial is to study how effective and safe the study medicine, elranatamab, is for the potential treatment of relapsed/refractory multiple myeloma. Participants must have previously tried, but not had success with, at least three types of multiple myeloma treatments.
This trial is currently open and accepting patients.
This clinical trial seeks to enroll approximately 150 patients, and will be organized into two separate groups, also called cohorts. Participants will be placed into one of two cohorts based on whether they have previously received therapies that target BCMA, a protein commonly found on the surface of multiple myeloma cells.
If you’re interested in participating, you will review and sign the informed consent document and continue with the screening process, to confirm whether you’ve met all eligibility criteria. The screening period will take up to 28 days.
If you’ve met all eligibility criteria, the study’s treatment period begins. You will stay in the hospital for the first and second dose of the study medicine, so that your health can be monitored by the study team. The study medicine will be given by a medical professional as an injection under the skin. Everyone who takes part in the study will receive the study medicine (there is no placebo).
For the next six months, you will see the study doctor and receive the study medicine at weekly visits. The study team will perform physical exams and other tests to monitor your health. After the initial six months, the dosing schedule may be adjusted. If the study doctor sees that your multiple myeloma has progressed or if you experience any side effects that are difficult to manage, the study medicine will be discontinued.
Approximately one month after the last dose of study medicine, there will be a final visit so the study team can observe your health. After that, the study team will contact you by phone (or you may have a visit) about once every three months for up to five years to check on your health.
Reasonable travel arrangements, including hotel accommodations and ground transportation may be covered. Please discuss this with the site staff for details.
The following criteria is a partial list of reasons why patients may be eligible to participate in this clinical trial. Further evaluation with a medical professional is required.
If you are not sure which treatments you have received, please ask your doctor.
Enrollment: 150 patients (estimated)View More
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Beverly Hills, CA
Boiling Springs, SC
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