This is a Phase I open-label, multicenter study designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary activity of tiragolumab administered as a single agent or in combination with daratumumab or rituximab in participants with relapsed or refractory (R/R) multiple myeloma (MM) or R/R non-Hodgkin lymphoma (NHL).
SparkCures ID | 1063 |
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Trial Phase | Phase 1 |
Enrollment | 52 Patients |
Treatments |
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Trial Sponsors |
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NCT Identifier |
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The following criteria is a partial list of reasons why patients may or may not be eligible to participate in this clinical trial. Further evaluation with a medical professional will be required to determine full eligibility.
The following criteria is provided for health care professionals.
Inclusion Criteria:
General Inclusion Criteria (All Participants):
Inclusion Criteria Specific to Arms A and C (R/R MM)
Inclusion Criteria Specific to Arms B and D (R/R NHL)
Exclusion Criteria:
General Exclusion Criteria (All Participants)
Exclusion Criteria Specific to Arms A and C (R/R MM)
Exclusion Criteria Specific to Arms B and D (R/R NHL)
Other protocol defined inclusion/exclusion criteria could apply
The following is a listing of trial locations that are open and accepting patients.
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Deer Park, OH
Philadelphia, PA
Nashville, TN
Fairfax, VA
The following is a listing of trial locations that are not currently open and accepting patients.
Deer Park, OH
Philadelphia, PA
Nashville, TN
Fairfax, VA
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