A Trial of TTI-621 for Patients With Hematologic Malignancies and Selected Solid Tumors

Overview

This is a trial of TTI-621 in subjects with relapsed or refractory hematologic malignancies and selected solid tumors.

SparkCures ID 896
Trial Phase Phase 1
Enrollment 270 Patients
Treatments
Trial Sponsors
  • Trillium Therapeutics Inc.
NCT Identifier

NCT02663518

Am I Eligible?

The following criteria is a partial list of reasons why patients may or may not be eligible to participate in this clinical trial. Further evaluation with a medical professional will be required to determine full eligibility.

Inclusion Criteria:

  1. Advanced measurable malignancy
  2. Adequate hematologic status
  3. Relapsed or refractory disease after at least 1 prior systemic treatment for the primary malignancy and not a candidate for other curative treatment
  4. Adequate coagulation function
  5. Adequate hepatic function
  6. Adequate renal function

Exclusion Criteria:

  1. Known, current central nervous system disease involvement or untreated brain metastases
  2. Allogeneic transplant within 30 days prior to the planned start of treatment or subjects with active graft-vs-host disease with the exception of Grade 1 skin involvement
  3. History of hemolytic anemia or bleeding diathesis

US Trial Locations

Accepting Patients

The following is a listing of trial locations that are open and accepting patients.

Verified John Theurer Cancer Center<br />Hackensack Meridian Health

SparkCures Verified Accurate, up-to-date information. Learn more


Mayo Clinic (Jacksonville)

Jacksonville, FL

Mayo Clinic (Rochester)

Rochester, MN

University of Pittsburgh Medical Center (UPMC)

Pittsburgh, PA

Tennessee Oncology
Centennial Clinic

Nashville, TN

Seattle Cancer Care Alliance

Seattle, WA

California
Colorado
Florida
Mayo Clinic (Jacksonville)

Jacksonville, FL

Minnesota
Mayo Clinic (Rochester)

Rochester, MN

New Jersey
Verified John Theurer Cancer Center<br />Hackensack Meridian Health

SparkCures Verified Accurate, up-to-date information. Learn more

New York
Ohio
Oregon
Pennsylvania
University of Pittsburgh Medical Center (UPMC)

Pittsburgh, PA

Tennessee
Tennessee Oncology
Centennial Clinic

Nashville, TN

Washington
Seattle Cancer Care Alliance

Seattle, WA

Resources

There are no resources, links or videos to display for this clinical trial.